• Biomarker-disease-therapy triplets
• Therapies
• Biomarkers
• Cancer types

• A
• Acral melanoma - Common cancer
  MET
• Acute lymphoblastic leukaemia - Rare cancer
  ABL1, ALK, CD19, CD20, DHFR, ERBB2, FGFR1, JAK2, KMT2A, XPO1
• Acute myeloid leukaemia - Rare cancer
  ABL1, BRAF, CD33, ERBB2, FGFR1, FLT3, IDH1, IDH2, KIT, KMT2A, KRAS, NF1, NRAS, PTEN, PTPN11, RAD21, SF3B1, SMC3, SRSF2, STAG2, TP53, U2AF1
• Acute promyelocytic leukaemia - Rare cancer
  XPO1
• Adenoid cystic carcinoma - Rare cancer
  KIT, MYB, NOTCH1
• Aggressive fibromatosis - Rare cancer
  APC, CTNNB1
• Ampullary carcinoma - Rare cancer
  ERBB2
• Anal cancer - Rare cancer
  HPV genotype
• Anaplastic astrocytoma - Rare cancer
  IDH1, Mismatch repair, Tumour Mutational Burden
• Anaplastic ganglioglioma - Rare cancer
  BRAF
• Anaplastic large cell lymphoma - Rare cancer
  ALK, CD30
• Anaplastic pleomorphic xanthoastrocytoma - Rare cancer
  RAF1
• Anaplastic thyroid cancer - Rare cancer
  BRAF, MTOR, TSC2
• Appendiceal cancer - Rare cancer
  GNAS, KRAS
• Appendiceal carcinoma - Rare cancer
  KRAS
• Atypical teratoid rhabdoid tumor - Rare cancer
  EZH2, RB1, SMARCB1

• B
• Basal cell carcinoma - Common cancer
  GLI1, GLI2, PTCH1, SMO, SUFU
• Biliary tract cancer - Rare cancer
  BRAF, CDKN2A, ERBB2
• Biliary tract cancers - Rare cancer
  BRAF, CD274, ERBB2
• Bladder cancer - Common cancer
  ERBB2
• Blastic plasmacytoid dendritic cell neoplasm - Rare cancer
  CD123
• Breast adenocarcinoma - Common cancer
  KRAS
• Breast cancer - Common cancer
  AKT1, AKT3, ALK, AR, AR+ESR1, ARID1A, ATM, BARD1, BCL2, BCL6, BRCA1, BRCA1+ERBB2, BRCA2, CCNE1, CDH1, CDK4, CDK6, CHEK2, EIF4EBP1, ERBB2, ERBB2+ERBB3, ERBB2+ESR1, ERBB3, ESR1, ESR1+CCNE1, ESR1+ERBB2, ESR1+ERBB2+PIK3CA, ESR1+MDM2, ESR1+PIK3CA, ESR1+TP53, FAM175A, FGFR1, FGFR2, HRAS, Homologous Recombination Deficiency Score, Intrinsic subtype, KAT6A, KRAS+NRAS+BRAF, MAP3K1+PIK3CA, MRE11A, MTOR, NRAS, NRG1, PALB2, PAXIP1, PGR, PIK3CA, PIK3CA+ESR1+ERBB2, PIK3CA+FGFR1, PIK3CA+FGFR2, PTEN, PTEN+ERBB2, RAD50, RAD51C, RB1, RIF1, SPEN, TACSTD2, TOP1, TP53BP1, Tumour Mutational Burden, XRCC2
• Breast secretory carcinoma - Common cancer
  NTRK1, NTRK2, NTRK3

• C
• Cancer of unknown primary - Rare cancer
  FGFR2, KRAS, NRAS, Tumour Mutational Burden
• Central nervous system cancer - Rare cancer
  NTRK1, NTRK2, NTRK3
• Cervical cancer - Uncommon cancer
  CD274, EGFR, ERBB2, ERCC1, FGFR2, FGFR2 , FGFR3, HPV genotype, NECTIN4, Tumour Mutational Burden
• Cholangiocarcinoma - Rare cancer
  BAP1, BRAF, CDKN2A, ERBB2, ERRFI1, FGFR2, FGFR3, IDH1, IDH2, KRAS, MDM2+TP53, NRAS, NRG1
• Chondrosarcoma - Rare cancer
  IDH1, IDH2
• Chordoma - Rare cancer
  SMARCB1
• Chronic eosinophilic leukaemia - Rare cancer
  JAK2, PDGFRA
• Chronic lymphocytic leukaemia - Rare cancer
  ATM, ATR, BCL2, CD20, TP53
• Chronic myelogenous leukaemia - Rare cancer
  ABL1, BAP1, LZTR1, NF1, PTPN11, WT1, XPO1
• Chronic myelomonocytic leukaemia - Rare cancer
  SF3B1, SRSF2
• Clear cell renal cell carcinoma - Rare cancer
  BAP1
• Colon adenocarcinoma - Common cancer
  KRAS
• Colorectal adenocarcinoma - Common cancer
  ALK, APC, APC+PIK3CA, ARID1A, ATM, ATR, B2M, BRAF, BRAF+KRAS, BRAF+MAP2K1, BRAF+MET, BRAF+NRAS, Consensus molecular subtype, EGFR, ERBB2, ERBB2+KRAS, ERBB3, FBXW7, FLT3, HRAS, IRS2, IRS2+BRAF, IRS2+KRAS, Immunoscore IC, KRAS, KRAS+ERBB3, KRAS+Microsatellite Instability, KRAS+Mismatch repair, KRAS+NRAS, MAP2K1, MET, MGMT, MLH1, MYB, MYC, Microsatellite Instability, Microsatellite instability+Mismatch repair, Mismatch repair, NF1, NRAS, PIK3CA, PIK3R2, POLD1, POLE, PTEN, RET, RNF43, ROS1, RSPO1, TP53, TP53+KRAS, Tumour Mutational Burden, Tumour Mutational Burden+Microsatellite, Tumour Mutational Burden+Mismatch repair
• Colorectal cancer - Common cancer
  CEACAM5, EGFR, ERBB2, ERBB2+KRAS, FGFR1, KRAS, POLD1, POLE
• Colorectal neuroendocrine carcinoma - Common cancer
  BRAF
• Cutaneous T-cell lymphoma - Rare cancer
  CCR4, CD30

• D
• Dedifferentiated liposarcoma - Rare cancer
  CALB1, CDK4, MDM2+TP53
• Dermatofibrosarcoma protuberans - Rare cancer
  PDGFB
• Desmoplastic small round cell tumours - Rare cancer
  WT1
• Diffuse astrocytoma - Rare cancer
  FGFR1
• Diffuse hemispheric glioma - Rare cancer
  H3F3A
• Diffuse Intrinsic Pontine Glioma - Rare cancer
  H3F3A, PPM1D
• Diffuse large B-cell lymphoma - Rare cancer
  BCL6, CD19, CD79B, EZH2, KLHL6, MYD88
• Diffuse Midline Glioma - Rare cancer
  H3F3A, TP53

• E
• Endometrial cancer - Uncommon cancer
  AKT1, ARID1A, BRAF, CCNE1, ERBB2, ESR1, FGFR1, FGFR2, FGFR2 , FGFR3, Homologous Recombination Deficiency Score, KRAS, MCL1, Microsatellite Instability, Microsatellite instability+Mismatch repair, Mismatch repair, PGR, PIK3CA, PIK3R1, PTEN, TP53, Tumour Mutational Burden
• Endometrial carcinoma - Uncommon cancer
  KRAS, MET
• Endometrioid endometrial cancer - Uncommon cancer
  ERBB2, ESR1, PGR
• Ependymoma - Rare cancer
  NF2, NTRK2
• Epithelial-myoepithelial carcinoma - Rare cancer
  HRAS
• Epithelioid haemangioendothelioma - Rare cancer
  CAMTA1, IDH2, WWTR1, YAP1
• Epithelioid hemangioendothelioma - Rare cancer
  IDH1, IDH2
• Epithelioid sarcoma - Rare cancer
  EZH2, RB1, SMARCB1
• Erdheim-Chester disease - Rare cancer
  BRAF
• Ewing sarcoma - Rare cancer
  FLI1
• Extramammary Paget’s disease - Rare cancer
  ERBB2, ERBB2+PTEN, ERBB3, MET
• Extrapulmonary neuroendocrine carcinoma - Rare cancer
  DLL3

• F
• Fallopian tube carcinoma - Uncommon cancer
  BRCA1, BRCA2, FOLR1, Homologous Recombination Deficiency Score, Loss-of-heterozygosity score
• Follicular lymphoma - Rare cancer
  CD20, EZH2
• Follicular thyroid cancer - Rare cancer
  BRAF

• G
• Gallbladder cancer - Common cancer
  ATM, CDKN2A, ERBB2, MTAP
• Gastric cancer - Common cancer
  ARID1A, BRAF, CCND1, CD274, CLDN18, CLDN18+ERBB2, CLDN6, EGFR, ERBB2, ERBB2+CD274, ERBB3, FGFR2, FGFR3, HGF, KRAS, MET, Microsatellite Instability, PIK3CA, PTEN, RICTOR, TP53, Tumour Mutational Burden
• Gastroesophageal junction adenocarcinoma - Common cancer
  CCND1, CD274, CLDN18, CLDN18+ERBB2, EGFR, ERBB2, ERBB2+CD274, FGFR2, KRAS, MET, Microsatellite Instability, PIK3CA, PTEN, TP53
• Gastrointestinal neuroendocrine carcinoma - Rare cancer
  BRAF
• Gastrointestinal stromal tumour - Rare cancer
  CDKN2A, KIT, NF1+KIT, PDGFRA
• Gastrooesophageal carcinoma - Uncommon cancer
  Tumour Mutational Burden
• Glioblastoma - Rare cancer
  ABL1, ATM, BRAF, CDK4, CDKN2A, EGFR, FGFR1, FGFR3, IDH1, IDH2, KIT, MDM2+TP53+IDH1, MET, MGMT, MSH2, Mismatch repair, NF1, NOTCH2, PIK3CA, PIK3R1, PMS2, PTEN, Tumour Mutational Burden
• Glioma - Rare cancer
  AR, BRAF, EGFR, IDH1, IDH2
• Gliomas - Rare cancer
  BRAF
• Glioneuronal tumour - Rare cancer
  BRAF
• Granulosa cell tumour - Rare cancer
  PGR

• H
• H3K27M-mutant glioma - Rare cancer
  H3F3A
• Hairy cell leukaemia - Rare cancer
  BRAF
• Head and neck squamous cell carcinoma - Rare cancer
  AKT1, BRCA1, CD274, EGFR, ERBB4, FANCC, HPV genotype, HRAS, Human Papillomavirus Status, MAPK1, MET, RB1
• Hemangioblastoma - Rare cancer
  VHL
• Hepatobiliary cancers - Rare cancer
  Tumour Mutational Burden
• Hepatocellular carcinoma - Rare cancer
  CD274, CRKL, FGF19, FGFR4, GPC3
• High-grade glioma - Rare cancer
  BRAF
• High-grade gliomas - Rare cancer
  ALK, BRAF, H3F3A, IDH1, KRAS, Mismatch repair, NF1, NTRK1, NTRK2, NTRK3, Tumour Mutational Burden
• High-grade well-differentiated neuroendocrine tumour - Rare cancer
  SEZ6
• Histiocytic sarcoma - Rare cancer
  MET
• Histiocytosis - Rare cancer
  ALK, ARAF, BRAF, KRAS, MAP2K1, MAP2K2, NRAS, PTPN11, RAF1
• Hodgkin’s lymphoma - Rare cancer
  CD20, CD30
• HPV16-positive cancers - Rare cancer
  HPV genotype

• I
• Inflammatory myofibroblastic tumour - Rare cancer
  ALK
• Intimal sarcoma - Rare cancer
  PDGFRA
• Intrahepatic cholangiocarcinoma - Rare cancer
  IDH1

• J
• Juvenile myelomonocytic leukaemia - Rare cancer
  CBL, KRAS, NRAS, PTPN11

• L
• Langerhans cell histiocytosis - Rare cancer
  BRAF
• Langerhans cell sarcoma - Rare cancer
  RASA1
• Liposarcoma - Rare cancer
  FRS2
• Liquid cancers - Rare cancer
  BCL2, IDH2, JAK1, JAK2, MYC, MYCN, SF3B1, SLC1A5, TP53
• Low-grade glioma - Rare cancer
  BRAF, CDKN2A, EGFR, IDH1, IDH2
• Low-grade gliomas - Rare cancer
  BRAF, IDH1, IDH2, NTRK1, NTRK2, NTRK3, RAF1
• Low-grade serous ovarian cancer - Uncommon cancer
  BRAF, KRAS, MAP2K1
• Low-grade serous ovarian carcinoma - Uncommon cancer
  PGR
• Low-grade spindle cell neoplasm - Rare cancer
  BRAF, CDKN2A
• Lung adenocarcinoma - Common cancer
  BRAF, ERBB2, FGFR1, KRAS, MET, RET
• Lung squamous cell carcinoma - Common cancer
  ATM, ATR, BRCA1, BRCA2, CCND1, CCND2, CCND3, CDK4, CDK6, CHEK1, ERBB2, FANCC, FANCM, FGFR1, FGFR2, FGFR3, MET, NRG1, PALB2, PIK3CA, TP63

• M
• Malignant peripheral nerve sheath tumor - Rare cancer
  MTAP, NF1, NF1+MET, NF1+SUZ12
• Malignant peripheral nerve sheath tumour - Rare cancer
  CD274
• Malignant rhabdoid tumor - Rare cancer
  SMARCA4
• Mammary analogue secretory carcinoma - Rare cancer
  NTRK1, NTRK2, NTRK3
• Mantle cell lymphoma - Rare cancer
  CD20
• Marginal zone lymphoma - Rare cancer
  CD20
• Mastocytosis - Rare cancer
  KIT, PDGFRA
• Medullary thyroid cancer - Rare cancer
  BRAF, FGFR1, MET, RET
• Medulloblastoma - Rare cancer
  NTRK3, PTCH1, SMO
• Melanoma - Common cancer
  ARID2, B2M, BRAF, BRCA2, BRD7, CTNNB1+KIT, ERBB4, FBXW7, HLA-A+PMEL, HLA-A2, HLA-A2+PRAME, JAK1, JAK2, KIT, KRAS, MAP2K1, MAP2K1+BRAF, MAP2K2, MAPK1, MAPK3, NF1, NRAS, PBRM1, RAF1
• Meningioma - Rare cancer
  CDKN2A, NF2
• Merkel cell carcinoma - Rare cancer
  TP53
• Mesothelioma - Rare cancer
  BAP1, BRCA1, CDKN2A, ERCC1, MRE11A, MSLN, MTAP, NF2
• Metaplastic breast carcinoma - Common cancer
  PIK3CA
• Mixed phenotype acute leukaemia - Rare cancer
  KMT2A
• Multiple myeloma - Rare cancer
  BRAF, CD38, KDM6A, SLAMF7, TNFRSF17
• Mycosis fungoides - Rare cancer
  CCR4
• Myelodysplastic/myeloproliferative diseases - Rare cancer
  FGFR1, PDGFRA, PDGFRB
• Myelodysplastic syndrome - Rare cancer
  IDH2, RAD21, SF3B1, SMC3, SRSF2, STAG2, TP53
• Myelofibrosis - Rare cancer
  JAK2
• Myeloproliferative diseases - Rare cancer
  FGFR1
• Myxoid liposarcoma - Rare cancer
  CTAG1B

• N
• Nasopharyngeal carcinoma - Rare cancer
  CD276
• Neuroblastoma - Rare cancer
  ALK, ATRX, BARD1, DLK1, MYC, MYCN, NRAS
• Neuroendocrine carcinoma - Rare cancer
  BRAF, DLL3, SEZ6, Tumour Mutational Burden
• Neuroendocrine tumour - Rare cancer
  SSTR2, Tumour Mutational Burden
• Non-clear cell renal cell carcinoma - Rare cancer
  SETD2
• Non-Hodgkin’s lymphoma - Common cancer
  CD20, EZH2
• Non-melanoma skin cancer - Common cancer
  Tumour Mutational Burden
• Nonseminoma - Rare cancer
  Chromosome
• Non-small cell lung cancer - Common cancer
  ALK, ARAF, ATM, BCL2L11, BRAF, BRAF+EGFR, BRAF+KRAS, BRAF+MAP2K1, BRAF+NRAS, BRAF+PTEN, BRCA1, BRCA2, CD274, CD274+EGFR+ALK, CD276, CDKN2A, CEACAM5, CLDN6, CRKL, DNMT3A, EGFR, EGFR+ALK, EGFR+BRAF, EGFR+CD274, EGFR+EGFR, EGFR+ERBB2, EGFR+MET, EGFR+MET+ALK, EGFR+MET+BRAF, EGFR+MET+KRAS, EGFR+RB1, EGFR+RBM10, EGFR+RET, EGFR+ROS1, EGFR+TP53, ERBB2, ERBB3, ERBB4, FANCD2, FBXW7, FGFR2, FGFR3, GNAS, KEAP1, KEAP1+KRAS, KRAS, KRAS+ERBB3, KRAS+MET, KRAS+NRAS+BRAF, KRAS+STK11, KRAS+TP53, Loss-of-heterozygosity score, MAP2K1, MET, MET+TP53, MRAS, MTAP, NF1, NOTCH3, NRAS, NRG1, PIK3CA, RASA1, RB1, RBM10, RET, ROS1, ROS1+MET, SMARCA4, STK11, STK11+KRAS, TOP1, Tumour Mutational Burden
• Non-small cell lung carcinoma - Common cancer
  CD274
• Non-vestibular schwannoma - Rare cancer
  NF2
• NUT carcinoma - Rare cancer
  BRD3, BRD4, NUTM1

• O
• Oesophageal adenocarcinoma - Uncommon cancer
  CD274, ERBB2, FGFR2, KRAS, MET
• Oesophageal cancer - Uncommon cancer
  CD274, NECTIN4
• Oesophageal squamous cell carcinoma - Uncommon cancer
  CD274, LGALS1, NTRK1
• Osteosarcoma - Rare cancer
  Mutational signature
• Ovarian cancer - Uncommon cancer
  ARID1A, ATM, BRAF, BRCA1, BRCA1+BRCA2, BRCA2, CCNE1, CD274, CDH6, CDK12, CLDN6, EMSY, ERBB2, ERCC1, FGFR2, FOLR1, Homologous Recombination Deficiency Score, KRAS, KRAS+NRAS+BRAF, Loss-of-heterozygosity score, MSLN, NRG1, PALB2, RAD50, RAD51C, RAD51D, ROS1, SETD2
• Ovarian clear cell carcinoma - Uncommon cancer
  ARID1A
• Ovarian mucinous carcinoma - Uncommon cancer
  ERBB2
• Ovarian small cell carcinoma - Uncommon cancer
  SMARCA2, SMARCA2+SMARCA4, SMARCA4

• P
• Paediatric low grade gliomas - Rare cancer
  BRAF
• Pancreatic acinar cell carcinoma - Rare cancer
  KRAS, RAF1
• Pancreatic adenocarcinoma - Uncommon cancer
  ARID1A, ARID1B, ATM, BRAF, BRCA1, BRCA2, CCL11, CDKN2A, CLDN18, EGFR, ERBB2, FANCD2, FANCG, FGFR1, FGFR2, KDM6A, KRAS, MDM2+TP53, Mismatch repair, NOTCH3, NRG1, NTRK1, PALB2, PBRM1, PTEN, RAD51C, RNF43, ROS1, SF3B1, SMARCA4, SMARCB1, STK11, TP53
• Pancreatic cancer - Rare cancer
  BRCA1, BRCA2, PALB2, RAD51C, RAD51D, Tumour Mutational Burden
• Pancreatic neuroendocrine tumour - Rare cancer
  MGMT, SSTR2, VHL
• Papillary craniopharyngioma - Rare cancer
  BRAF
• Papillary renal cell carcinoma - Rare cancer
  FH, HGF, MET, NF2
• Papillary thyroid cancer - Rare cancer
  BRAF, ROS1
• Paraganglioma - Rare cancer
  EPAS1, RET, SDHA, SDHB
• Penile cancer - Rare cancer
  EGFR
• Peritoneal mucinous carcinomatosis - Uncommon cancer
  GNAS
• Peritoneal serous carcinoma - Uncommon cancer
  BRCA1, BRCA2, FOLR1, Homologous Recombination Deficiency Score, Loss-of-heterozygosity score
• Perivascular epithelioid cell tumour - Rare cancer
  TSC1, TSC2
• Phaeochromocytoma - Rare cancer
  RET, SDHA, SDHB
• Pilocytic astrocytoma - Rare cancer
  RAF1
• Pituitary adenoma - Rare cancer
  STK11
• Polycythemia vera - Rare cancer
  EPAS1, JAK2
• Prostate cancer - Common cancer
  AR, ATM, AURKA, BARD1, BRCA1, BRCA2, BRIP1, CD276, CDK12, CHEK1, CHEK2, ERBB3, FANCA, FANCG, FANCI, FANCL, FGFR2, MYCN, Microsatellite Instability, Mismatch repair, NBN, PALB2, PIK3R1, PPP2R2A, PSMA, PTEN, RAD51B, RAD51C, RAD51D, RAD54L, RB1, STEAP1, TP53, TP53+RB1, Tumour Mutational Burden, Tumour Mutational Burden+Microsatellite Instability, Tumour Mutational Burden+Mismatch repair
• Prostate small cell carcinoma - Common cancer
  ALK, DLL3

• R
• Renal cell carcinoma - Uncommon cancer
  ALK, CDH6, FLCN, MTOR, PBRM1, PTEN, TSC1, TSC2, VHL
• Rhabdoid tumors - Rare cancer
  SMARCB1
• Rhabdomyosarcoma - Rare cancer
  CDK4, KRAS, NRAS
• Round cell liposarcoma - Rare cancer
  CTAG1B

• S
• Salivary duct carcinoma - Rare cancer
  HRAS
• Salivary gland cancer - Rare cancer
  ERBB2
• Salivary gland cancers - Rare cancer
  AR, BRAF, ERBB2, HRAS, Tumour Mutational Burden
• Sarcoma - Rare cancer
  BRAF, NF2, PDGFRA, Tumour Mutational Burden
• Sarcomatoid renal cell carcinoma - Rare cancer
  NF2
• Seminoma - Rare cancer
  Chromosome
• Small-cell lung cancer - Common cancer
  BCL2, CD276, CHEK1, DLL3, IRS2, MET, MYC, MYCL, MYCN, POU2F3, SEZ6, Tumour Mutational Burden
• Small intestine adenocarcinoma - Rare cancer
  BRAF
• SMARCA4-deficient thoracic sarcoma - Rare cancer
  SMARCA4
• Soft tissue sarcomas - Rare cancer
  PDGFRA
• Solid tumour - Rare cancer
  AKT1, ATM, ATR, BRAF, BRCA1, BRCA2, BRIP1, CCND1, CCND2, CCND3, CD8, CDK4, CDK6, CDKN2A, CHEK2, EGFR, ERBB2, ERBB3, FGFR1, FGFR2, FGFR3, GNA11, GNAQ, HRAS, KRAS, MET, MTAP, NF1, NRAS, PTEN, RAD50, RET, ROS1, SEZ6, TP53
• Solid tumours - Rare cancer
  AKT1, AKT2, ALK, AR, ARAF, ARID1A, ARID2, ATM, ATM+TP53, ATRX, BAP1, BARD1, BCL2, BCL2L1, BRAF, BRCA1, BRCA2, BRD4, CCND1, CCND2, CCND3, CCNE1, CD274, CD276, CDK12, CDK4, CDK6, CDKN2A, CDKN2A+MTAP, CEACAM5, CHEK1, CLDN18, CLDN6, DAXX, EGFR, EGFR+ERBB3, EGFR+ERRFI1, EPHA7, ERBB2, ERBB2+KRAS, ERBB3, EZH2, F3, FANCA, FAT1, FBXW7, FGFR1, FGFR2, FGFR3, FGFR4, FOLR1, GNA11, GNAQ, Globo H, HLA-A, HRAS, IDH1, IDH2, KIT, KRAS, LRP1B, MAP2K1, MAP2K4, MAP3K1, MCL1, MDM2, MET, MET+KRAS, MGMT, MLH1, MSH2, MSH6, MSLN, MTAP, MTORC1, MUC1, MYB, MYC, MYCN, Microsatellite Instability, Mismatch repair, NECTIN4, NF1, NF2, NOTCH1, NRAS, NRG1, NTRK1, NTRK2, NTRK3, PBRM1, PDCD1LG2, PIK3CA, PIK3R1, PMS2, POLD1, POLE, PRKCA, PRKCB, PRKDC, PTCH1, PTEN, PTPN11, RAC1, RAD51C, RAD51D, RAF1, RB1, RET, RIT1, RNF43, ROS1, SF3B1, SLC1A5, SLC39A6, SLX4, SMARCA4, SMARCB1, SMO, SUZ12, TACSTD2, TP53, TSC1, TSC2, Tumour Mutational Burden, VCTN1
• Solitary fibrous tumour - Rare cancer
  FGFR1, FGFR2
• Somatostatinoma - Rare cancer
  EPAS1
• Spindle cell sarcoma - Rare cancer
  RAF1
• Subependymal giant cell astrocytoma - Rare cancer
  TSC1, TSC2
• Synovial sarcoma - Rare cancer
  CTAG1B, SS18
• Sézary syndrome - Rare cancer
  CCR4

• T
• T-cell acute lymphoblastic leukaemia - Rare cancer
  ABL1
• Tenosynovial giant cell tumor - Rare cancer
  CSF1
• Testicular cancer - Rare cancer
  CLDN6
• Thymic carcinoma - Rare cancer
  CD274, KIT, PBRM1
• Thymic neuroendocrine carcinoma - Rare cancer
  KIT
• Thymoma - Rare cancer
  PBRM1
• Thyroid cancer - Rare cancer
  EIF1AX, EIF1AX+NRAS, RET, Tumour Mutational Burden
• Triple-negative breast cancer - Common cancer
  AKT1, AR, ATM, BRAF, BRCA1, BRCA1+BRCA2, BRCA2, CCNE1, CD274, CDK12, DAXX, EGFR, ERBB2, ESR1+ERBB2, MET, Molecular subtype, NECTIN4, NF1, NOTCH2, PIK3CA, PTEN, RAD51, RB1, TACSTD2, Tumour microenvironment
• Type 1 neurofibromatosis - Rare cancer
  NF1
• Type 2 neurofibromatosis - Rare cancer
  NF2

• U
• Urothelial carcinoma - Common cancer
  ARID1A, ATM, BARD1, BRCA1, BRCA2, BRIP1, CD274, CDK12, CDKN2A, CXCL13, EGFR+ERBB3, ERBB2, ERBB3, ERCC2, FGFR1, FGFR2, FGFR3, HRAS, KMT2C, MTOR, NECTIN4, NF2, RAD51C, TSC1
• Uterine carcinosarcoma - Rare cancer
  ERBB2, POLE
• Uterine leiomyosarcoma - Rare cancer
  BRCA2, BRCA2+PTEN, RAD51
• Uterine serous carcinoma - Rare cancer
  BRIP1, ERBB2, Homologous Recombination Deficiency Score, TP53
• Uveal melanoma - Common cancer
  BAP1, GNA11, GNAQ, HLA-A+PMEL, HLA-A2

• V
• Vaginal cancer - Rare cancer
  HPV genotype
• Vestibular schwannoma - Rare cancer
  NF2
• Vulvar cancer - Rare cancer
  HPV genotype, Tumour Mutational Burden

• W
• Waldenstroms macroglobulinaemia - Rare cancer
  CD20, CXCR4, MYD88
• Well-differentiated liposarcoma - Rare cancer
  CDK4, MDM2+TP53